We observed that Myc positively modulated genes involved in single and double-strand DNA-repair process, which was paralleled by an enhanced capability of TNBC BRCAmut BC cells and BCSphCs to accumulate nuclear Rad51 foci following exposure to 8 Gy of radiation therapy (Fig. 3A, B and Supplementary Fig. S3A, B). This evidence concerns the gene RAD51 and breast cancer.