Although both subtypes are significantly up-regulated in the plasma of COVID-19 patients (Fig. 1E), only IFNA2 levels correlate with the IFN-α scores (Fig. 1F) and with mRNA expression of well recognized IFN-inducible genes (ISGs), such as ISG15 and OAS2 (Fig. 1G). The gene discussed is IFNA2; the disease is COVID-19.