Transcranial magnetic stimulation (TMS) studies on hyperexcitability in C9orf72 patients with either FTD, ALS or ALS-FTD and asymptomatic C9orf72 carriers, showed abnormalities in ALS patients and were inconclusive for FTD, possibly due to a low sample size (Schanz et al., 2016). The gene discussed is C9orf72; the disease is frontotemporal dementia.