PDCD2L and cancer: Ozdemir et al. have reported that depletion of CAF can augment pancreas cancer growth, which suggests that CAF may play a anti-tumor role in some tumors [32].Our above study showed that PDCD2L expression was negatively correlated with CAF in many cancers including BRCA, BRCA-Basal, LUSC, SARC, STAD and TGCT.