PDCD2L and pachyonychia congenita: Figure 5B showed the relationship between PDCD2L expression and apoptosis in PC, PDCD2L expression and cell cycle in RCC, and PDCD2L expression and invasion in AML.PDCD2L expression profiles were shown in single cells of PC, RCC and AML by T-SNE diagram (Fig. 5C).The results suggest that PDCD2L might play a crucial role in the process of cancer progression.