Accordingly, serum levels of NT-proBNP, which decreased significantly 1-year after LVAD implantation in the Control-group (9692 ± 8816 pg/ml at baseline vs. 1988 ± 1590 pg/ml at 1-year; p < 0.001), remained significantly higher in the MR-group (10,336 ± 8360 pg/ml at baseline vs. 7297 ± 10,682 pg/ml at 1-year; p = 0.262) (p = 0.024) (Table 4). Here, NPPB is linked to miotic rate.