Currently, both the National Comprehensive Cancer Network (NCCN) guidelines and European Society for Medical Oncology (ESMO) guidelines recommend genetic testing for BRCA1 and BRCA2 genes to women also with personal history of cancer (e.g. multiple primary BCs, if first diagnosis was ≤50 years old, early age of BC, co-occurrence of BC and OC, etc. [167]. This evidence concerns the gene BRCA2 and breast cancer.