Further post hoc tests revealed that when compared to the HC group, both the BD manic episodes group and the BD depressive episodes group had increased MPV, RDW, and RPR values (P < 0.05), and decreased platelet counts, PDW, PCT, albumin and PLR values (P < 0.05); furthermore, the BD manic episodes group showed higher neutrophil counts and SII values than the HC group (P < 0.05) when BD depressive episodes group had no differences in neutrophil, SII with HC group (P > 0.05). This evidence concerns the gene ALB and manic or hypomanic episode.