Endocrine work-up revealed low cortisol levels at 1.17 μg/dL (reference: 4.82–19.5 μg/dL) and inappropriately normal adrenocorticotropic hormone levels at 12.4 pg/mL (reference: 0.1–46.0 pg/mL), indicating secondary adrenal insufficiency. The gene discussed is POMC; the disease is Adrenal insufficiency.