In addition, urinary TTR levels did not differ between patients with and without a clinical history of ischemia and presence of cardiovascular risk factors and clinical characteristics such as atrial fibrillation and pulmonary hypertension, either in the total ADHF group or when the subgroups without and with renal dysfunction at admission were separately considered (see Supplementary Table S6). Here, TTR is linked to pulmonary arterial hypertension.