CD70 mRNA levels were significantly increased by cytokine treatment in both RA FLS (0.009 ± 0.001 versus no treatment 0.001 ± 0.001; n = 3) and OA FLS (0.014 ± 0.002 versus no treatment 0.003 ± 0.001; n = 4) (Figure 1A). This evidence concerns the gene CD70 and rheumatoid arthritis.