FMR1 and fragile X syndrome: Of interest is the finding that both ASD patients and ASD mouse models (FMRP) displayed surprising GABA dysregulations and glutamate receptor subunit changes, even in post-mortem cerebella of ASD subjects, without FXS or FMRP being downregulated, which was associated with increased levels of mGluR5 and decreased levels in GABA-A β3 subunits [92].