Interestingly, studies have shown contradictory results with those of Song et al. [34] and Zhan et al. [13] supporting a favourable prognosis, whereas Hoshino et al. [12] and Huang et al. [11] indicated a negative HOXB9 prognostic role in patients with high HOXB9 levels and with CRC after bowel resection. The gene discussed is HOXB9; the disease is colorectal carcinoma.