Acetylation has been found by Wan et al. to be an important post-translational modification of HOXB9, resulting in the downregulation of its target gene jumonji domain-containing protein 6 (JMJD6), and subsequently causing a suppression in tumour growth and the migration of in lung adenocarcinoma in vitro [37]. The gene discussed is HOXB9; the disease is lung adenocarcinoma.