Another single cell-sequencing analysis of lung adenocarcinoma samples defined two main types of intratumor cells: the first similar to epithelial alveolar cells, the second with upregulation of EGFR and JAK/STAT pathways and increased stimulation of the EMT process by transforming growth factor β (TGFβ) and hypoxia-corelated factors [19,20,28]. Here, TGFB1 is linked to lung adenocarcinoma.