GTF3C1 and breast carcinoma: To explore TFIIIC chromatin behavior in several human cell lines, we used TFIIIC genome-wide ChIP-seq data from fetal lung fibroblasts (IMR90), normal mammary gland epithelial cells (MCF10A), infiltrating ductal carcinoma breast cancer cells (T47D) [19], and human embryonic stem cells (hESCs) (see Materials and Methods for details).