ATI as the primary lesion of COVID-19-associated AKI is also consistent with a urinary-biomarker study demonstrating that COVID-19 patients with stage 2 and 3 AKI have elevated levels of urinary [TIMP-2] • [IGFBP7] and tubular (α-1-microglobulin) proteinuria [24,78]. The gene discussed is TIMP2; the disease is acute kidney injury.