SLC4A5 and retinal detachment: Given that SLC4A5 transport functions have been documented in epithelial tissues [18,19,20,21,22,23] and that retinal detachment in mice is associated with RPE dysfunction [31,32,33], we considered the hypothesis that a loss of SLC4A5 function in the RPE might contribute to the reported retinal detachment and accompanying ocular phenotypes in Slc4a5 mutant mice.