The expression of BCL-2 in lymphomas has been widely reported, the t (14:18) translocation generates a constitutive expression of BCL-2 derived from the juxtaposition of BCL-2 with the immunoglobulin heavy chain promoter in follicular lymphoma [31], and in 30% diffuse large B-cell lymphoma [32]. This evidence concerns the gene BCL2 and diffuse large B-cell lymphoma.