As a result, our model could be a representation of the affected pathways that differ between LMS and LM, where the genes associated with alterations in the extracellular matrix suggest the diagnosis of LM (since COL4A5, ITGA9, and MFAP5 are the only genes overexpressed in LM), and the genes associated with defective DNA replication or DNA damage repair or segregation of chromosomes suggest the diagnosis of LMS. This evidence concerns the gene ITGA9 and lymphangioma.