AKT1 and neoplasm: Certain miRNAs were found to be key regulators of well-established carcinogenic pathways such as miR-143 and miR-145, acting as tumor suppressors on the p53/c-Myc pathway [5,6], the circular RNA (circRNA) Cdr1as sequestering miR-7, reducing its ability to regulate the proto-oncogenic PI3K/AKT pathway [7,8], and the long noncoding RNA (lncRNA) GAS5-controlling mTOR-mediated proliferation via the competitive binding of glucocorticoid receptors and miR-21 [9,10].