CP and neoplasm: The physical and topical examination of induced tumor in the breast tissue revealed significant progression of disease and size of the tumor in the positive control, Pacli and Au-P groups, whereas reduced tumor size was observed in groups that received individual treatments with Cur and Au-C, but the groups that received combinational treatments (CP, Au-CP) demonstrated the efficacy of combinational therapy against the induced tumor progression and metastasizing tumor cells (Figure 5a,b).