DEPTOR and diabetes mellitus: Computational analysis revealed that tRFs modified in the sperm of obese males can potentially regulate 62 genes whose expression is altered in eight-cell embryos injected with RNAs isolated from the HFD F0 group, including Maea (macrophage erythroblast attacher, E3 ubiquitin ligase), Ccnc (cyclin C), and Deptor (DEP domain containing MTOR interacting protein), which are known regulators of β-cell function and/or associated with diabetes [95,96].