Many immune-derived cytokines and chemokines, including IL-17, IL-23, IL-6, C-X-C motif ligand-1 (CXCL-1), TNF-α, and p65, can drive inflammatory cell infiltration and an inflammation loop, thus regulating keratinocyte proliferation and leading to the development and maintenance of psoriasis [4]. This evidence concerns the gene TNF and psoriasis.