These data also agree with the oxidative stress status, osteocyte apoptosis and the high levels of FGF23 in chronic kidney disease (CKD) [53,54,55], as well as the increase of apoptotic osteocytes related to the enhancement of FGF23 in glucocorticoid-induced osteoporosis, with consequent decrease in mineralization processes [39]. This evidence concerns the gene FGF23 and chronic kidney disease.