In another study, alpha-1-acid glycoprotein 1 (AGP1) was found upregulated in PDAC tissues compared to normal pancreatic tissue obtained from patients with benign pancreatic disease such as serous cystadenoma, mucinous cystadenoma and pancreatic pseudotumor via NPLC-MS/MS and later, verified by PRM [186]. This evidence concerns the gene ORM1 and mucinous cystadenoma.