CFB and breast carcinoma: For instance, acute phase proteins including α1-antitrypsin, α1-antichymotrypsin (ACT), complement factor B (CFB) and leucine-rich glycoprotein (LRG) proteins were previously reported to be enhanced in PanC, while upregulated levels of ACT, CFB and clusterin as well as decreased levels of kininogen in patients with breast cancer [165].