PLG and Parkinson disease: The Gene Ontology analysis of the 128 CR proteins identified in both ND- and R-GBM pools highlighted that, in addition to the already mentioned blood coagulation and plasminogen activating cascade, other pathways resulted as being over-represented, namely, asparagine and aspartate biosynthesis, de novo purine biosynthesis, fructose galactose metabolism, glycolysis, Parkinson disease, pyruvate metabolism and TCA cycle (Figure 9).