SPP1 and acute kidney injury: Urinary KIM-1 and urinary clusterin were also the best biomarkers for predicting moderate-level histopathological damage at day 3 (AUC 0.82 (95% CI 0.70–0.95), p = 0.037 and 0.801 (0.67–0.93), p = 0.060, respectively) and day 6 (AUC 0.91 (0.79–1.00) and 0.86 (0.74–1.00), respectively), while urinary osteopontin was also a good biomarker for predicting VA-AKI [62].