As FGFR1, FGFR2, RIP5, and HIP2 proteins are expressed in all parts of the nephron and some in the renal vasculature, it is justifiable to speculate about their significance in the maintenance of overall homeostasis and the maturation of kidney structures, as well as their contribution in the occurrence of different kidney pathologies. Here, DSTYK is linked to urogenital neoplasm.