As a matter of fact, the last two decades of research have provided evidence for a role of FAK in promoting different types of tumors, including the most common adult breast cancer and hepatocellular carcinoma (HCC), but also pediatric cancers such as Ewing sarcoma and rhabdomyosarcoma (ref. [9] and reviewed in [10,11,12]). Here, PTK2 is linked to breast carcinoma.