Finally, we were surprised that despite only ~10% of monocytic cells establishing a latent infection [48,49], we observed drastic changes in cleaved caspase-3 protein levels in the total cell population (Figure 3 and Figure 5), coupled with virus-induced protection from high ROS levels in all cells analysed (Figure 4). The gene discussed is CASP3; the disease is disease arising from reactivation of latent virus.