In addition, further studies regarding the role of C. pinnatifida on the interactions between the gut and liver in the management of hepatic steatosis are needed as the extract decreases hepatic total cholesterol levels by impeding cholesterol absorption from the gut through the suppression of fibroblast growth factor receptor 4 (FGFR4) mRNA and protein. This evidence concerns the gene FGFR4 and fatty liver disease.