After adjustment, however, for age, sex, race, ethnicity, education level, economic status, BMI, smoking status, diabetes, hypertension, caffeine consumptions, ALT, alcohol consumption, high-density lipoprotein cholesterol, c-reactive protein, transferrin saturation, sedentary lifestyle, and total energy intake, the HEI became significantly and inversely associated to the prevalence of NAFLD in a dose-dependent manner (ptrend = 0.028). The gene discussed is CRP; the disease is diabetes mellitus.