Consistent with these findings, in PCa cells, Brg1 is recruited to the ELOVL3 promoter by the retinoic acid receptor-related orphan receptor (RORγ) and interacts with the acetyltransferase p300, promoting H3K27Ac to activate ELOVL3 expression [244]. The gene discussed is SMARCA4; the disease is posterior cortical atrophy.