The multivariate Cox regression analysis adjusted by HD vintage, hypertension, the type of vascular access, use of RAS inhibitors and statins, the comorbidity index, hemoglobin level, and log CRP revealed that the GNRI and mCI were significant indictors for all-cause mortality (GNRI: adjusted HR (aHR), 0.89; 95% CI, 0.86–0.92, p < 0.0001; mCI aHR, 0.83; 95% CI, 0.76–0.90, p < 0.0001) (Table 2). The gene discussed is CRP; the disease is hypertensive disorder.