As a result, it was discovered that mutations leading to overexpression of EGFR genes (e.g., increased regulation or amplification) are significantly associated with many cancers: lung granuloma (40% of cases), rectal tumors, glioblastoma (50%), and epithelial carcinomas of the head and neck (80–100%) [47,48]. This evidence concerns the gene EGFR and glioblastoma.