In one study, β-asarone reduced the APP, PS1, Aβ, BACE1, and p62 levels while increasing the SYN1, BECN1, and LC3 levels in PC12 cell AD models, suggesting that β-asarone protects the PC12 cell model against Aβ42 by promoting autophagy [89]. This evidence concerns the gene MAP1LC3A and Alzheimer disease.