The beneficial effects of the extract led to a significant reduction in the incidence of cataracts in the rats, a phenomenon which was believed to be associated with reductions in oxidative stress and inflammation, indicated by lower levels of malondialdehyde, prostaglandin E2, and tumor necrosis factor-α (TNF-α); attenuated vascular permeability was also observed due to decreased levels of vascular endothelial growth factor. The gene discussed is TNF; the disease is cataract.