Regarding toxicities, one cardiac SAE (hypertension) and three different types of AEs were noted: blood and lymphatic system disorders (abnormalities in ALT/AST, neutrophils/granulocytes), gastrointestinal disorders (diarrhea), and general disorders (fatigue, asthenia, lethargy, malaise, and nausea). This evidence concerns the gene GPT and lymphatic system disorder.