Overall, we identified 23 (9.5%) exclusive cases of recent dengue (IgM and/or NS1 positive), 102 (42.1%) were considered as chikungunya exclusive cases by the detection of specific antibody and/or viral genome, and in 76 (31.4%) patients, the co-detection of chikungunya and recent dengue exposure (here, named chikungunya/dengue) was reported. Here, CD40LG is linked to dengue disease.