It has been shown that mir-548-3p has decreased significantly in breast cancer, and its overexpression has inhibited proliferation and promoted apoptosis of breast cancer cells when inhibition was performed by regulating the expression of enoyl coenzyme A hydratase short chain 1 (ECHS1), showing the potential of mir-548-3p as a therapeutic target for breast cancer [37]. The gene discussed is ECHS1; the disease is breast carcinoma.