ENSG00000235059 and infection: The enrichment of two main domains in the encoded genes during infection was highlighted during analysis, i.e., NACHT domain which possesses NTPase activity [89] and is found in NLRs that recognize microbial and viral components [90], and genes encoding PRY-SPRY domains present in multiple proteins of innate immunity [91], suggesting that proteins containing such domains may act as pathogen sensors and promote the establishment of antiviral responses in fish.