Up-regulated differentially expressed genes (DEGs) indicated a clear relationship with the innate immune response against viral infection, including genes coding PRRs (LPG2 or DHX58) and IFN-stimulated genes (ISG15, Mx, STAT1, HERC5, IFI44, IFIT-1, NUP133, TRIM21). The gene discussed is IFI44; the disease is viral infectious disease.