KNG1 and infection: Among the myriad prosurvival factors that are known to prevent abortive infection by triggering the anti-apoptotic Akt pathway, bradykinin and endothelin are potential candidates [68,69] in light of evidence that intracardiac parasitism in mice is fueled via activation of bradykinin (B2) and endothelin (ETA/ETB) receptors [21,22].