Kaurenoic acid, an ent-kaurene-type diterpene exhibits antiproliferative effect in breast, gastric, 293T, HeLa, PANC-1, and cervical cell lines by inducing apoptosis in tumor cells through regulation of the c-FLIP, caspase-3, caspase-8, and miR-2 pathways [95] The presence of these phytochemicals in JM fractions as observed in GC-MS are responsible for the anticancer effect of J. procera. The gene discussed is CASP8; the disease is neoplasm.