Glycyrrhizin, a compound extracted from licorice root, was studied by Sun Y. et al. (2018) [146] who showed that glycyrrhizin had an anti-inflammatory effect against MS through suppressing microglial M1 activation via reducing TGF-β1, IFN-γ, TNF-α, IL-17A, and IL-6 cytokines while increasing IL-4 [146]. This evidence concerns the gene IL6 and myeloid sarcoma.