Moreover, the liver of vaccination-protected mice responds to blood-stage malaria with a similar early down- and up-regulation of the expression of the genes Myh10 (p-value < 0.01), Lama1 (p-value < 0.05), Lamb1 (p-value < 0.05), Notch4 (p-value < 0.05), Cxcl12 (p-value < 0.05), Kit (p-value < 0.05), and Vwf (p-value < 0.05). The gene discussed is CXCL12; the disease is malaria.