For this purpose, the SARS-CoV-2 spike (S) protein is a promising lead, since is the major structural protein anchored at the exterior of the membrane of native viruses, carries B cell and T cell epitopes and is the main target for neutralizing antibodies generated from natural infection that protect against viral infection and currently approved COVID-19 vaccines [19,20]. The gene discussed is CHMP5; the disease is COVID-19.