Another study conducted by Wei and collaborators (2019) [56] reported the proteolysis of this kinase and inhibition of p-Akt (Ser473) in pancreatic cancer (PANC-1 and MIA PaCa-2) cell lines exposed to epigallocatechin-3-gallate and gemcitabine treatment. The gene discussed is AKT1; the disease is familial pancreatic carcinoma.