Brain-derived tau oligomers from AD and dementia with Lewy bodies (DLB) were internalized through HSPG-mediated endocytosis using cortical neurons isolated from C57BL/6 mice, while those from PSP were internalized through not only HSPG-mediated endocytosis but also through alternative mechanisms [30]. Here, MAPT is linked to supranuclear palsy, progressive, 1.