On one hand there is the inability of the Nbs to trigger antibody-dependent cell cytotoxicity (photoimmunotherapy), while on the other hand EGFR-targeted Nbs demonstrated quicker accumulation in the tumor, a more homogenous distribution throughout the tumor, and a faster clearance of unbound molecules—ideal characteristics for delivering a photosensitizer. The gene discussed is EGFR; the disease is neoplasm.