The global PD, calculated using the Mahalanobis distance (MD) [11] and including 14 biomarkers (mean corpuscular hemoglobin [MCH], red cell distribution width [RDW], red blood cell [RBC], platelets, percentage of lymphocytes, white blood cell [WBC], C-reactive protein [CRP], potassium, sodium, hemoglobin, albumin, alanine transaminase [ALT], aspartate aminotransferase [AST], and total protein), appeared to be one of the best predictors for death and deterioration of patients with COVID-19. This evidence concerns the gene CRP and COVID-19.