In the case of G-CSF, there were no significant changes between the subgroups (male MDD patients and HCs: 64.62±11.33pg/mL and 63.92±10.89pg/mL, respectively, p = 0.965; female MDD patients and HCs: 46.93±8.99pg/mL and 41.64±5.63pg/mL, respectively, p = 0.611). This evidence concerns the gene CSF3 and major depressive disorder.